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Horopito (Pseudowintera colorata) is only found in New Zealand and is one of the oldest surviving flowering plants having survived 65 million years because of the superb natural chemical defence system in its leaves. It is a strong antioxidant and contains the sesquiterpene compound polygodial, best known for its antimicrobial, antifungal and anti-inflammatory properties. The subcanopy of native forests provides ideal conditions for the growth of yeasts and fungi, which is why Horopito has developed such outstanding natural defences in its leaves against these organisms. Active Horopito™ oleoresin is a rich source of polygodial.